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Beilstein J. Org. Chem. 2018, 14, 1840–1845, doi:10.3762/bjoc.14.157
Graphical Abstract
Scheme 1: The chemical structures of (a) bisphosphonates (BPs) and (b) guanidinium-modified calix[5]arene (GC...
Scheme 2: Schematic illustration of the binding between BPs and GC5A and the operating IDA principle of fluor...
Scheme 3: The chemical structures of the selected BP drugs.
Figure 1: (a) Fluorescence competitive titration of GC5A·Fl (0.9/1.0 μM) with risedronate (up to 29.6 μM) in ...
Figure 2: The set-up calibration lines of the fluorescence intensities for quantitatively determining the con...